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Laboratory of Health Science

Faculty of Applied Pharmaceutical Sciences
We investigate the mechanisms by which the disruption of the circadian rhythm induces obesity and related diseases. We have found that BMAL1, a core transcriptional factor in biological clock system, regulates energy metabolism in a tissue dependent manner, and the dysfunction of BMAL1 induces various disorders such as hyperlipidemia, diabetes, lack of long-term memory etc. These data may provide novel information on chronotherapy.

Laboratory of Health Science